Reprogram Biosciences Closes Seed for Tumor Cell Reprogramming

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Reprogram Biosciences, a preclinical oncology biotechnology company developing mRNA-based therapeutics for solid tumors, has closed its Seed financing. The company announced the close on May 27, 2026, which brings total capital raised to $6 million since its founding in 2025.

Investors in the round include Unshackled Ventures, 1517 Fund, and Narya. Proceeds will support continued development of the company’s lead program, expansion of its AI discovery engine, and CMC activities.

Reprogram Biosciences is developing a new class of therapeutics based on in situ cell reprogramming. In this approach, mRNA-encoded gene combinations are delivered directly into the tumor, where they activate the immune system by inducing antigen-presenting function in tumor cells.